100&Change: 2020

Improving Global Health by Repurposing Essential Medicines Internationally (Remedi)

Uncover new therapeutic uses for the 376 medicines on WHO’s Essential Medicines List and amplify availability of existing and new uses to benefit priority populations.

DOWNLOAD: Project Factsheet
Two-page overview of proposal
Competition Participation
100&Change: 2020
Current Work Location
  • Tennessee, United States
Proposed Work Locations:
  • Kano State, Nigeria
  • Ādīs Ābeba Āstedader, Ethiopia
  • Federal District, Brazil
  • National Capital Territory of Delhi, India
  • Gauteng, South Africa
Priority Populations:
  • Adults
  • Economically disadvantaged people
  • People with diseases and illnesses
Sustainable Development Goals (SDGs):
  • 3. Good health and well-being

Executive Summary:

The World Health Organization (WHO) Essential Medicines List (EML) defines minimum acceptable availability of 376 safe, affordable medicines. Over 150 countries use the EML to guide treatment decisions. However, its utility is hindered - the number of diseases addressed is limited and pathways to spread information are under-powered. As a result, billions of people in low- and middle-income countries (LMICs) have inadequate access to treatments for serious illnesses. Our program, Remedi, will uncover additional uses of EML medicines, and catalyze the EML’s global reach by enhancing its format, accessibility, and health worker awareness. We will make better use of what we have. We will systematically curate, validate, share, and locally implement existing and new therapeutic uses, prioritizing the most prevalent medicines for diseases with the highest current and projected future burden, affecting the most vulnerable and marginalized. Hundreds of millions of people will benefit from medicines already in local pharmacies.

Organization Details
Lead Organization

Vanderbilt University Medical Center

website: https://victr.vumc.org/
Organization Headquarters
Davidson County, Tennessee, United States
Organization ID
Annual Operating Budget
> $1 Billion
Number of Full-time Employees
> 1,000

Charity, fund, non-governmental organization, religious institution, school, or other entity