100&Change: 2021

Johns Hopkins University

Zero TB Kids: Ending the Pediatric Tuberculosis Epidemic

Tuberculosis, a leading killer of children globally, can be eliminated with an ambitious program of community mobilization, novel intervention strategies, and innovative new biomedical tools.

Submitted: August 2019
DOWNLOAD: Project Factsheet
Two-page overview of proposal
Competition Participation
100&Change: 2021
Current Work Location(s):
  • State of Tamil Nādu, India
  • State of Mahārāshtra, India
  • State of Himāchal Pradesh, India
  • State of Mahārāshtra, India
  • State of Tamil Nādu, India
  • State of Himāchal Pradesh, India
Priority Population(s):
  • Infants and toddlers
  • Children
  • Adolescents
Sustainable Development Goals (SDGs):
  • 3. Good health and well-being
  • 10. Reduced inequalities

Executive Summary

TB is a leading killer of children worldwide. Tools to control TB have existed for decades but are poorly implemented. While ending TB in adults is stalled, pediatric TB is uniquely ripe for elimination. We have led development of innovative tools and strategies for controlling childhood TB: •Finding, treating, and preventing TB in school-age children •Preventing TB in children exposed in the household •Finding and treating TB in pregnant women to prevent transmission to newborns We use cutting-edge molecular diagnostics and short-course preventive regimens to diagnose, treat, and prevent TB in children with social mobilization campaigns to engage affected communities. In just 2 years, we have reduced TB prevalence in Tibetan refugee schoolchildren by ~60%. Our project will benefit children who are refugees, have HIV, live in slums, and are poor. Over 5 years, we can eliminate TB in children across India, with major health, economic, and cultural benefits.

Organization Details
Lead Organization

Johns Hopkins University

website: http://www.hopkinsmedicine.org
Organization Headquarters
Baltimore County, Maryland, United States
Organization ID
Annual Operating Budget
> $1 Billion
Number of Full-time Employees
> 1,000

Charity, fund, non-governmental organization, religious institution, school, or other entity